When you can’t afford to get it wrong… capillary electrophoresis enables accurate, unambiguous results for targeted genomic analysis.

Analysis of nucleic acids using capillary electrophoresis (CE) is performed via two methods: Sanger sequencing and fragment analysis.  Both provide simple, sample-to-answer workflows for highly accurate sequence interrogation and fast turnaround time.

 Sanger sequencing

Gold-standard technology for accurate sequence determination with single-base resolution. Ideal for targeted sequencing and confirmation analysis.

Learn how Sanger sequencing supports various applications:

Download Sanger Sequencing guide ›
Explore the simple Sanger sequencing workflow ›

Fragment analysis

Simple, most time efficient 4-step method for multiplexed detection of pathogens, variants, SNPs or size analysis.

Take DNA analysis further with fragment analysis applications:

Download Fragment Analysis Applications guide ›
Explore the 4-step fragment analysis workflow ›

Instruments and kits for genetic analysis

Applied Biosystems capillary electrophoresis products provide end-to-end workflow solutions for Sanger sequencing and fragment analysis and include genetic analyzers, reagents, and software. 

Capillary electrophoresis applications  

Blue ATGC pattern with human head and DNA pattern

Applications in clinical research environments

Sanger sequencing and fragment analysis are foundational applications in a range of clinical environments from clinical research to clinical reference labs

Vial containing DNA helix

mRNA manufacturing QC

Sequence confirmation is critical during mRNA therapeutic and vaccine manufacturing. Trust Sanger sequencing to get it right

DNA helix with portion pulled out

Gene editing confirmation

Simple Sanger sequencing and fragment analysis assays for genotypic validation of CRISPR, TALENs, and prime editor genome engineering

SARS-CoV-2 virus on ATCG background

SARS-CoV-2 research & characterization

Gold standard Sanger sequencing for identification, surveillance, and characterization of emerging viruses like SARS-CoV-2


New to capillary electrophoresis? Learn more about these technologies and how scientists are using them to get answers to complex and challenging questions.

For education and application see our CE training resources,learning center, and publications.

Video: Sanger sequencing and fragment analysis using CE: beyond expectations

Style Sheet for Global Design System

For Research Use Only. Not for use in diagnostic procedures.